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Resistance of cells biochemically transformed by herpes simplex virus DNA fragments to thymidine and deoxyadenosine cytotoxicity

✍ Scribed by Saul Kit; Mary Michalak; Haruki Otsuka

Book ID
119406706
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
324 KB
Volume
95
Category
Article
ISSN
0006-291X

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✍ Saul Kit; Marion Hazen; Haruki Otsuka; Hamida Qavi; David Trkula; Del Rose Dubbs πŸ“‚ Article πŸ“… 1981 πŸ› John Wiley and Sons 🌐 French βš– 994 KB

## Abstract To analyze the site of integration of the herpes simplex virus type 1 (HSV‐1) thymidine kinase (TK) gene in biochemically transformed human cells, TK‐HeLa‐(BU25) cells were transformed to the TK^+^ phenotype by a cloned, 2 kbp Pvull fragment of HSV‐1 DNA. The transformed cells [HeLa(BU2