## Abstract A transformed mouse cell line (H238) was obtained following the infection of 238 mouse cells with ultraviolet (UV) irradiationโinactivated herpes simplex virus type 2 (HSVโ2). The transformed cells produced tumors with a 100% incidence within 8 weeks in 6โweekโold syngeneic BALB/c mice
โฆ LIBER โฆ
Biochemical transformation of mouse cells by herpes simplex virus types 1 and 2: Comparison of different methods for inactivation of viruses
โ Scribed by F. Rapp; Nancy Turner
- Publisher
- Springer Vienna
- Year
- 1978
- Tongue
- English
- Weight
- 1010 KB
- Volume
- 56
- Category
- Article
- ISSN
- 1432-8798
No coin nor oath required. For personal study only.
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## Abstract Six oncogenically transformed cell lines were obtained following infection of hamster embryo fibroblasts with UVโirradiated herpes simplex virus type 2 (HSVโ2) or with an HSVโ2 temperatureโsensitive mutant. All lines produced undifferentiated fibrosarcomas in newborn hamsters, four of t