Polymorphisms of thymidine kinase gene i
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Kudo, E.; Shiota, H.; Naito, T.; Satake, K.; Itakura, M.
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Article
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1998
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John Wiley and Sons
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English
⚖ 416 KB
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Drug-resistance of herpes simplex virus (HSV) is caused most frequently by mutation of the viral thymidine kinase (TK) gene. To elucidate the significance of detecting nucleotide changes of the TK gene for screening drug-resistant viruses, the frequency and variation of the genetic polymorphisms in