Requirement for glycogen synthase kinase-3β in cell survival and NF-κB activation
✍ Scribed by Hoeflich, Klaus P.; Luo, Juan; Rubie, Elizabeth A.; Tsao, Ming-Sound; Jin, Ou; Woodgett, James R.
- Book ID
- 109770162
- Publisher
- Nature Publishing Group
- Year
- 2000
- Tongue
- English
- Weight
- 352 KB
- Volume
- 406
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/35017574
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## Abstract Glycogen synthase kinase 3β (GSK3β) activity is regulated by phosphorylation processes and regulates in turn through phosphorylation several proteins, including eukaryotic initiation factor 2B (eIF2B). Serine 9 phosphorylation of GSK3β (pGSK3βSer9), usually promoted by activation of the
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