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On the Role of Phosphatidylinositol 3-Kinase, Protein Kinase B/Akt, and Glycogen Synthase Kinase-3β in Photodynamic Injury of Crayfish Neurons and Glial Cells

✍ Scribed by Maxim A. Komandirov; Evgeniya A. Knyazeva; Yulia P. Fedorenko; Mikhail V. Rudkovskii; Denis A. Stetsurin; Anatoly B. Uzdensky

Book ID
107575437
Publisher
Humana Press Inc
Year
2011
Tongue
English
Weight
369 KB
Volume
45
Category
Article
ISSN
0895-8696

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## Abstract Excitotoxicity and cell death induced by glutamate are involved in many neurodegenerative disorders. We have previously demonstrated that excitotoxicity induced by millimolar concentrations of glutamate in hippocampal slices involves apoptotic features and glutamate‐induced glutamate re