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Report of an HIV and HHV-8 negative case of primary effusion lymphoma with idiopathic T4 lymphocytopenia

✍ Scribed by Nikolaos J. Tsagarakis; Aspasia Argyrou; Georgios Gortzolidis; Nektaria Kentrou; Stefanos I. Papadhimitriou; Konstantina Tzanetou; Georgios Kakiopoulos; Konstantinos A. Papadimitriou; Dimitra Skoumi; Georgios Paterakis

Book ID: 107618794
Publisher: Carden Jennings Publishing
Year: 2009
Tongue: English
Weight: 269 KB
Volume: 90
Category: Article
ISSN: 0925-5710
DOI: 10.1007/s12185-009-0343-0

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Primary effusion lymphoma (PEL) is a novel lymphoproliferative disorder associated with human herpesvirus 8 (HHV-8) infection. Most PELs develop in HIV-seropositive individuals and are nearly always positive for Epstein-Barr virus (EBV), a finding which obscures the role of HHV-8 in lymphomagenesis.