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HIV-negative, HHV-8-unrelated primary effusion lymphoma-like lymphoma: report of two cases

✍ Scribed by Tsuyoshi Takahashi; Akira Hangaishi; Go Yamamoto; Motoshi Ichikawa; Yoichi Imai; Mineo Kurokawa


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
388 KB
Volume
85
Category
Article
ISSN
0361-8609

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Primary effusion lymphoma (PEL) is a novel lymphoproliferative disorder associated with human herpesvirus 8 (HHV-8) infection. Most PELs develop in HIV-seropositive individuals and are nearly always positive for Epstein-Barr virus (EBV), a finding which obscures the role of HHV-8 in lymphomagenesis.