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Reply to “Gene-environment interaction influences the reactivity of autoantibodies to citrullinated antigens in rheumatoid arthritis”

✍ Scribed by Lundberg, Karin; Alfredsson, Lars; Källberg, Henrik; Mahdi, Hiba; Fisher, Benjamin A; Malmström, Vivianne; Venables, Patrick J; Klareskog, Lars


Book ID
109918112
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
86 KB
Volume
42
Category
Article
ISSN
1061-4036

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## Abstract ## Objective The functional role of HLA class II molecules in the pathogenesis of rheumatoid arthritis (RA) is unclear. HLA class II molecules are involved in the interaction between T and B lymphocytes required for long‐lived B cell responses and generation of high‐affinity IgG antibo