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Influence of HLA–DR genes on the production of rheumatoid arthritis–specific autoantibodies to citrullinated fibrinogen

✍ Scribed by Isabelle Auger; Mireille Sebbag; Christian Vincent; Nathalie Balandraud; Sandrine Guis; Leonor Nogueira; Björn Svensson; Alain Cantagrel; Guy Serre; Jean Roudier

Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
854 KB
Volume
52
Category
Article
ISSN
0004-3591

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✍ Floris A. Van Gaalen; Jill Van Aken; Tom W. J. Huizinga; Geziena M. Th. Schreude 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 90 KB 👁 2 views

## Abstract ## Objective The functional role of HLA class II molecules in the pathogenesis of rheumatoid arthritis (RA) is unclear. HLA class II molecules are involved in the interaction between T and B lymphocytes required for long‐lived B cell responses and generation of high‐affinity IgG antibo