Rheumatoid arthritis–specific autoantibodies to peptidyl arginine deiminase type 4 inhibit citrullination of fibrinogen
✍ Scribed by Isabelle Auger; Marielle Martin; Nathalie Balandraud; Jean Roudier
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 300 KB
- Volume
- 62
- Category
- Article
- ISSN
- 0004-3591
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📜 SIMILAR VOLUMES
## Abstract ## Objective Protein citrullination is an important posttranslational modification recognized by rheumatoid arthritis (RA)–specific autoantibodies. One of the citrullinating enzymes, peptidyl arginine deiminase type 4 (PAD‐4), is genetically associated with development of RA in some po
## Abstract ## Objective To address the ongoing debate concerning the specificity of synovial citrullinated proteins for rheumatoid arthritis (RA) and to analyze their pathophysiologic relevance to the induction or perpetuation of the RA‐specific anti–citrullinated protein antibodies (ACPAs). ##