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Reply to “a powerful test of sib-pair linkage for disease susceptibility”

✍ Scribed by Daniel J. Schaid; Todd G. Nick

Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
104 KB
Volume
8
Category
Article
ISSN
0741-0395

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Nick examines the problem of testing for linkage between a disease susceptibility locus and a marker locus for sib-pair data. Given a specified simple alternative for the parameters (pO, p I , p 2 ) of the multinomial distribution of (NO, N , , N2), where Nj denotes the number of sibs sharing exactl

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