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Reply: The bone-resorbing activity of interleukin-6

✍ Scribed by Maxine Gowen

Book ID
112118803
Publisher
American Society for Bone and Mineral Research
Year
2009
Tongue
English
Weight
128 KB
Volume
6
Category
Article
ISSN
0884-0431

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Interleukin-1 (IL-1) is one of the most potent boneresorbing factors involved in bone loss associated with inflammation. We previously reported that IL-1 prolonged the survival of multinucleated osteoclastlike cells (OCLs) formed in cocultures of murine osteoblasts/stromal cells and bone marrow cell