Interleukin-1 (IL-1) is one of the most potent boneresorbing factors involved in bone loss associated with inflammation. We previously reported that IL-1 prolonged the survival of multinucleated osteoclastlike cells (OCLs) formed in cocultures of murine osteoblasts/stromal cells and bone marrow cell
Interleukin 1 Induces Multinucleation and Bone-Resorbing Activity of Osteoclasts in the Absence of Osteoblasts/Stromal Cells
β Scribed by Eijiro Jimi; Ichiro Nakamura; Le T. Duong; Tetsuro Ikebe; Naoyuki Takahashi; Gideon A. Rodan; Tatsuo Suda
- Book ID
- 115603142
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 519 KB
- Volume
- 247
- Category
- Article
- ISSN
- 0014-4827
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract The present study was performed to examine the effect of the high concentration of extracellular calcium ([Ca^2+^]~e~) on osteoclastβlike cell formation and boneβresorbing activity in the presence or absence of osteoblasts. High [Ca^2+^]~e~ (3 and 5 mM) significantly stimulated osteocla
## Abstract We studied the effects of BMPβ7/OPβ1 on growth and differentiation of bone marrow stromal cells. BMS2, a mouse bone marrow stromal cell line capable of differentiating into adipocytes and osteoblasts, were treated in a serumβfree medium containing differentiation agents that favor the e