✦ LIBER ✦

Repeated administration of berberine inhibits cytochromes P450 in humans

✍ Scribed by Ying Guo; Yao Chen; Zhi-rong Tan; Curtis D. Klaassen; Hong-hao Zhou

Publisher: Springer
Year: 2011
Tongue: English
Weight: 152 KB
Volume: 68
Category: Article
ISSN: 0031-6970
DOI: 10.1007/s00228-011-1108-2

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Inhibition of human cytochrome P450 isof

Inhibition of human cytochrome P450 isoforms in vitro by zafirlukast

✍ Richard I. Shader; Brian W. Granda; Lisa L. von Moltke; Gina M. Giancarlo; David 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 135 KB 👁 1 views

Zafirlukast is a cysteinyl leukotriene antagonist used to treat allergic and exercise-induced asthma. This in vitro study used human liver microsomes to evaluate the inhibitory activity of zafirlukast versus six human cytochrome P450 (CYP) isoforms. Zafirlukast (0 -250 mM) was co-incubated with fixe

Inhibition and induction of human cytoch

Inhibition and induction of human cytochrome P450 enzymes: current status

✍ Olavi Pelkonen; Miia Turpeinen; Jukka Hakkola; Paavo Honkakoski; Janne Hukkanen; 📂 Article 📅 2008 🏛 Springer-Verlag 🌐 English ⚖ 790 KB

Microtiter Plate Assays for Inhibition o

Microtiter Plate Assays for Inhibition of Human, Drug-Metabolizing Cytochromes P450

✍ Charles L. Crespi; Vaughn P. Miller; Bruce W. Penman 📂 Article 📅 1997 🏛 Elsevier Science 🌐 English ⚖ 71 KB

termination of both storage carbohydrates in whole 1394. yeast cells was developed, which can be readily applied 4.

Potent inhibition of human cytochrome P4

Potent inhibition of human cytochrome P450 1 enzymes by dimethoxyphenylvinyl thiophene

✍ Sang-Kwang Lee; Yongmo Kim; Mie Young Kim; Sanghee Kim; Young-Jin Chun 📂 Article 📅 2004 🏛 Springer 🌐 English ⚖ 584 KB

Tight-binding inhibition by α-naphthofla

Tight-binding inhibition by α-naphthoflavone of human cytochrome P450 1A2

✍ Uhn Soo Cho; Eun Young Park; Mi Sook Dong; Bum Seok Park; Keehyuk Kim; Kyung Hyu 📂 Article 📅 2003 🏛 Elsevier Science 🌐 English ⚖ 429 KB

Human cytochrome P450 (P450) enzymes exhibit remarkable diversity in their substrate specificities, participating in oxidation reactions of a wide range of xenobiotic drugs. Previously, we reported that alpha-naphthoflavone (ANF) is bound to the recombinant P450 1A2 tightly and stabilizes an overall

Cytochrome P450-dependent toxicity of da

Cytochrome P450-dependent toxicity of dapsone in human erythrocytes

✍ Shobana Ganesan; Rajnish Sahu; Larry A Walker; Babu L. Tekwani 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 246 KB 👁 1 views

## Abstract The most prominent adverse effects seen during treatment with dapsone, an antibacterial and antiprotozoal agent, are hemolysis and methemoglobinemia. An __in vitro__ microsomal/cytochrome P~450~ (CYP)‐linked assay, which allows reactive metabolites generated __in situ__ to react with th