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Repair of DNA interstrand crosslinks: molecular mechanisms and clinical relevance

✍ Scribed by Peter J McHugh; Victoria J Spanswick; John A Hartley

Book ID
117782334
Publisher
The Lancet
Year
2001
Tongue
English
Weight
363 KB
Volume
2
Category
Article
ISSN
1470-2045

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## Abstract Host cell reactivation assay using Trioxsalen‐crosslinked plasmid pEGFP‐N1 showed that human cells were able to repair Trioxsalen interstrand crosslinks (ICL). To study the mechanism of this repair pathway, cells were transfected with the plasmids pEGFP‐1, which did not contain the prom