𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis and Molecular Modeling of a Nitrogen Mustard DNA Interstrand Crosslink

✍ Scribed by Angelo Guainazzi; Arthur J. Campbell; Dr. Todor Angelov; Prof. Carlos Simmerling; Prof. Orlando D. Schärer


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
419 KB
Volume
16
Category
Article
ISSN
0947-6539

No coin nor oath required. For personal study only.

✦ Synopsis


Dedicated to Prof. Francis Johnson on the occasion of his 80th birthday

[a] A.


📜 SIMILAR VOLUMES


Binding of nuclear proteins associated w
✍ Amy J. Warren; Michael A. Ihnat; Sara E. Ogdon; Erin E. Rowell; Joshua W. Hamilt 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 304 KB 👁 2 views

Mitomycin C (MMC) is a DNA crosslinking agent from human Xeroderma Pigmentosum (XP) complethat is used in cancer chemotherapy. Unlike the mentation group A and E cell lines, and a Fanconi's DNA crosslinks formed by cisplatin or psoralen, Anemia cell line were also examined. The UV-20 which significa

Alkylation of the dna of sensitive and r
✍ T. A. Connors; J. A. Double 📂 Article 📅 1970 🏛 John Wiley and Sons 🌐 French ⚖ 564 KB

## Abstract The concentration of ^3^H‐aniline mustard in two tumour lines has been measured and the level of binding of the drug to DNA followed for 48 hours after intraperitoneal injection. Although the two tumour lines differ a hundred‐fold in their sensitivity to this alkylating agent, no good c

Overexpression of GSTA2 protects against
✍ Jingping Xie; Keith Shults; Leanne Flye; Fen Jiang; David R. Head; Robert C. Bri 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 326 KB 👁 1 views

## Abstract The effectiveness of bifunctional alkylating nitrogen mustard compounds in chemotherapy is related to their ability to form DNA inter‐strand crosslinks. Patients exposed to DNA inter‐strand crosslinking (ICL) agents subsequently experience an elevated incidence of myelodysplastic syndro