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RENAL METABOLISM OF ACRYLONITRILE TO CYANIDE: IN VITRO STUDIES

✍ Scribed by A.M. MOSTAFA; A.B. ABDEL-NAIM; O. ABO-SALEM; A.H. ABDEL-AZIZ; F.M.A. HAMADA

Book ID
118770699
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
169 KB
Volume
40
Category
Article
ISSN
1043-6618

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Metabolism of methacrylonitrile to cyani
Metabolism of methacrylonitrile to cyanide: In vitro studies
✍ Farooqui, Mohammed Y. H. ;Diaz, Rolando G. ;Cavazos, Rogelio πŸ“‚ Article πŸ“… 1990 πŸ› John Wiley and Sons 🌐 English βš– 557 KB

In liver fractions from male Sprague-Dawley rats, the metabolism of methacrylonitrile (MeAN) to cyanide (CN-) was localized in microso-ma1 fraction and required reduced nicotinamide adenine dinucleotide phosphate (NADPH) and oxygen for maximal activity. The biotransformation of MeAN to CN-was charac