Lactoperoxidase catalyzes in vitro activation of acrylonitrile to cyanide
β Scribed by Sherry N. Nasralla; Asser I. Ghoneim; Amani E. Khalifa; Mohamed Z. Gad; Ashraf B. Abdel-Naim
- Book ID
- 119381777
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 434 KB
- Volume
- 191
- Category
- Article
- ISSN
- 0378-4274
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract The enzyme mercaptopyruvate sulfurtransferase appears to play an important role in the in vivo detoxification of cyanide. It does so by transferring sulfur to cyanide to produce thiocyanate, which is less toxic and may be excreted through the kidney. Several compounds were tested for th
In liver fractions from male Sprague-Dawley rats, the metabolism of methacrylonitrile (MeAN) to cyanide (CN-) was localized in microso-ma1 fraction and required reduced nicotinamide adenine dinucleotide phosphate (NADPH) and oxygen for maximal activity. The biotransformation of MeAN to CN-was charac