𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Renal imaging studies at 1.5 and 9.4 T: Effects of diuretics

✍ Scribed by Susanta K. Sarkar; George A. Holland; Robert E. Lenkinski; Mark A. Mattingly; Lewis B. Kinter


Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
600 KB
Volume
7
Category
Article
ISSN
0740-3194

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✦ Synopsis


We have studied the effects of two diuretics, selective for renal cortical (furosemide) and inner medullary (vasopressin antagonist) water handling, in rat kidney at 1.5 T and find that furosemide completely dissipates the cortical-inner medullary T2 gradient whereas the vasopressin antagonist has little effect. This phenomenon appears to be related to changes in luminal water content. We also demonstrate the feasibility of obtaining live mouse kidney images with a resolution of 100 x 100 x 700 micrometers at 9.4 T.


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