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Renal and hepatic accumulation of cadmium and lead in the expression of CYP4F2 and CYP2E1

✍ Scribed by Jason R. Baker; Robert J. Edwards; Jerome M. Lasker; Michael R. Moore; Soisungwan Satarug

Book ID
119378161
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
273 KB
Volume
159
Category
Article
ISSN
0378-4274

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## Abstract We report a comprehensive examination of rat hepatic CYP1A2 and CYP2E1 ontogeny. We compare the data to human data to determine the rat's capacity as a model to identify CYP‐mediated mechanisms underlying age‐dependent differences in susceptibility to toxicity. We evaluated CYP expressi