Remarkable effect of lithium bromide in the enantioselective protonation with α-sulfinyl alcohols

✍ Scribed by Gregorio Asensio; Pedro A. Aleman; Lius R. Domingo; Mercedes Medio-Simón

• Book ID: 104259133
• Publisher: Elsevier Science
• Year: 1998
• Tongue: French
• Weight: 270 KB
• Volume: 39
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(98)00469-9

✦ Synopsis

The favourable effect of lithium bromide enhancing the facial enantioselectivity in the protonation of methyl tetralone enolate with ct-sulfinyl alcohols is described. Theoretical calculations allow to propose a model to explain the stereochemical course of the protonation reaction.