A cloned, 40 kb, genomic DNA fragment, containing the last exon of the gene for human cytochrome c oxidase subunit VIb and its flanking sequences, was used as a probe to localize the subunit VIb gene on human metaphase chromosomes. The probe was labelled with Bio-11-dUTP and detected by fluorescence
โฆ LIBER โฆ
Relevance to prenatal diagnosis of the identification of a human Y/autosome translocation by Y-chromosome-specific in situ hybridisation
โ Scribed by Patricia M. Ellis; Dr. John D. West; Katrine M. West; Roderick S. Murray; M. Christine Coyle
- Book ID
- 111662083
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 835 KB
- Volume
- 25
- Category
- Article
- ISSN
- 1040-452X
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The authors report a case of a balanced 1;17 translocation with breakpoints located in the secondary constriction of chromosome 1. This translocation is associated with pathological symptoms similar to those observed following a proximal deletion of lq. We request contact with colleques who have obs