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Relevance of cyclin D1b expression andCCND1polymorphism in the pathogenesis of multiple myeloma and mantle cell lymphoma

✍ Scribed by Sophie Krieger; Juliette Gauduchon; Mikel Roussel; Xavier Troussard; Brigitte Sola

Book ID: 115010873
Publisher: BioMed Central
Year: 2006
Tongue: English
Weight: 374 KB
Volume: 6
Category: Article
ISSN: 1471-2407
DOI: 10.1186/1471-2407-6-238

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## Abstract 1q rearrangement is a remarkably frequent secondary chromosomal change in both non‐Hodgkin's lymphoma (NHL) and multiple myeloma (MM), where it is associated with tumor progression. To gain insight into 1q rearrangement‐associated disease mechanisms, we used fluorescence in situ hybridi