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Differential Expression of Cyclin D1 in Mantle Cell Lymphoma and Other Non-Hodgkin's Lymphomas

✍ Scribed by Nadine S. Ives Aguilera; Karen E. Bijwaard; Beverly Duncan; Amy E. Krafft; Wei-Sing Chu; Susan L. Abbondanzo; Jack H. Lichy; Jeffery K. Taubenberger

Book ID: 117022862
Publisher: American Society for Investigative Pathology
Year: 1998
Tongue: English
Weight: 271 KB
Volume: 153
Category: Article
ISSN: 0002-9440
DOI: 10.1016/s0002-9440(10)65710-0

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Centrocytic lymphoma, or mantle cell lymphoma (MCL), is characterized by a chromosomal translocation t( 11;14) (q13;q32) involving the bcl-1 locus on chromosome 11. Cyclin D1 is a cell-cycle regulatory protein essential for G 1 S transition and has been identified as a potential transforming gene af

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