Relationship of EMAST and Microsatellite Instability Among Patients with Rectal Cancer
β Scribed by Bikash Devaraj; Aaron Lee; Betty L. Cabrera; Katsumi Miyai; Linda Luo; Sonia Ramamoorthy; Temitope Keku; Robert S. Sandler; Kathleen L. McGuire; John M. Carethers
- Book ID
- 107412011
- Publisher
- Springer-Verlag
- Year
- 2010
- Tongue
- English
- Weight
- 436 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1091-255X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Work in our laboratory has shown a significantly higher frequency of microsatellite mutations in tumours from lungcancer patients with rare alleles at the Hras1 VNTR locus compared with those with common alleles. In 137 lungcancer patients, the association between microsatellite instability and rare
Hereditary non-polyposis colorectal cancer (HNPCC) is a dominantly inherited syndrome linked to DNA-mismatch-repair (MMR) gene defects, which also account for microsatellite instability (MSI) in tumour tissues. Diagnosis is based mainly on family history, according to widely accepted criteria (Amste
Microsatellite instability (MSI) is intrinsic to most colorectal carcinomas (CRC) from patients with hereditary nonpolyposis colorectal cancer (HNPCC), reflecting germline mutations in the mismatch-repair (MMR) genes. Its occurrence and chronological sequence of development in sporadic CRC appears l