Microsatellite instability among individuals of Hispanic origin with colorectal cancer
β Scribed by Samir Gupta; Raheela Ashfaq; Payal Kapur; Bianca B. Afonso; Thuy-Phuong T. Nguyen; Faryal Ansari; C. Richard Boland; Ajay Goel; Don C. Rockey
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 359 KB
- Volume
- 116
- Category
- Article
- ISSN
- 0008-543X
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## Abstract Highβfrequency microsatellite instability (MSIβH) due to defective DNA mismatch repair occurs in the majority of hereditary nonpolyposis colorectal cancers (HNPCCs) and in a subset of sporadic malignant tumors. Clinicopathologic and genotypic features of MSIβH colorectal tumors in HNPCC