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Relationship between the initial rate of protein aggregation and the lag period for amorphous aggregation

✍ Scribed by Borzova, Vera A.; Markossian, Kira A.; Kurganov, Boris I.

Book ID
121754876
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
439 KB
Volume
68
Category
Article
ISSN
0141-8130

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## Abstract Under favorable conditions, many proteins can assemble into macroscopically large aggregates such as the amyloid fibrils that are associated with Alzheimer's, Parkinson's, and other neurological and systemic diseases. The overall process of protein aggregation is characterized by initia