Absolute Correlation between Lag Time and Growth Rate in the Spontaneous Formation of Several Amyloid-like Aggregates and Fibrils

Insight into the correlation between lag

Insight into the correlation between lag time and aggregation rate in the kinetics of protein aggregation

✍ Stefan Auer; Dimo Kashchiev 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 407 KB

## Abstract Under favorable conditions, many proteins can assemble into macroscopically large aggregates such as the amyloid fibrils that are associated with Alzheimer's, Parkinson's, and other neurological and systemic diseases. The overall process of protein aggregation is characterized by initia