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Relationship between the expression of RASSF1A protein and promoter hypermethylation of RASSF1A gene in bladder tumor

โœ Scribed by Jianting Hu; Hongzhao Li; Taoping Shi; Xin Ma; Baojun Wang; Hua Xu; Xiang Ai; Zhenghua Ju; Chao Wang; Guoxi Zhang; Xu Zhang


Book ID
107405745
Publisher
Springer-Verlag
Year
2008
Tongue
Chinese
Weight
129 KB
Volume
28
Category
Article
ISSN
0510-9752

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High frequency loss of 3p21.3 region where RASSF1A located was demonstrated in several tumors. We aimed to investigate the methylation status of RASSF1A and the frequency of LOH in 3p21.3 region in bladder cancer. Three bladder cancer cell lines, 40 cases of bladder TCC and 14 cases of paired voided