Erratum to: Promoter hypermethylation of RASSF1A, MGMT, and HIC-1 genes in benign and malignant colorectal tumors
β Scribed by Hamdy E. Abouzeid; Abdel Meguid Kassem; Hatem A. El-mezayen; Hayaat Sharad; Shimaa Abdel Rahman; Abdel Hady Abdel Wahab
- Book ID
- 107693965
- Publisher
- S. Karger AG
- Year
- 2011
- Tongue
- English
- Weight
- 36 KB
- Volume
- 32
- Category
- Article
- ISSN
- 1010-4283
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High frequency loss of 3p21.3 region where RASSF1A located was demonstrated in several tumors. We aimed to investigate the methylation status of RASSF1A and the frequency of LOH in 3p21.3 region in bladder cancer. Three bladder cancer cell lines, 40 cases of bladder TCC and 14 cases of paired voided
## Abstract Aberrant promoter hypermethylation of tumorβassociated genes leading to their inactivation is a common event in many cancer types. Using a sensitive restrictionβmultiplex PCR method, we studied the promoter hypermethylation profile of the __p16, p15, hMLH1, MGMT__ and __Eβcad__ genes in