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Frequent hypermethylation of the RASSF1A gene in prostate cancer

โœ Scribed by Liu, Limin; Yoon, Jung-Hoon; Dammann, Reinhard; Pfeifer, Gerd P


Book ID
110066970
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
161 KB
Volume
21
Category
Article
ISSN
0950-9232

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High frequency loss of 3p21.3 region where RASSF1A located was demonstrated in several tumors. We aimed to investigate the methylation status of RASSF1A and the frequency of LOH in 3p21.3 region in bladder cancer. Three bladder cancer cell lines, 40 cases of bladder TCC and 14 cases of paired voided