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Relationship between Protein Stabilization and Protein Rigidification Induced by Mannosylglycerate

โœ Scribed by Tiago M. Pais; Pedro Lamosa; Bertrand Garcia-Moreno; David L. Turner; Helena Santos


Book ID
116664279
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
711 KB
Volume
394
Category
Article
ISSN
0022-2836

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โœ Tim J. Kamerzell; C. Russell Middaugh ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 330 KB

The ability to successfully formulate and manufacture therapeutic protein dosage forms requires a thorough understanding of their physico-chemical properties. Proteins are inherently dynamic molecules of marginal stability. These properties present unique challenges to the pharmaceutical scientist a