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The Inverse Relationship between Protein Dynamics and Thermal Stability

โœ Scribed by Tsai, Amos M.; Udovic, Terrence J.; Neumann, Dan A.

Book ID
118514204
Publisher
Biophysical Society
Year
2001
Tongue
English
Weight
146 KB
Volume
81
Category
Article
ISSN
0006-3495

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The ability to successfully formulate and manufacture therapeutic protein dosage forms requires a thorough understanding of their physico-chemical properties. Proteins are inherently dynamic molecules of marginal stability. These properties present unique challenges to the pharmaceutical scientist a