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Relationship between hybridoma growth and monoclonal antibody production

โœ Scribed by P.M. Hayter; N.F. Kirkby; R.E. Spier


Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
703 KB
Volume
14
Category
Article
ISSN
0141-0229

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Transient kinetics of hybridoma growth a
โœ Mina Dalili; David F. Ollis ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 587 KB

A quantitative study of the influence of initial serum concentration on hybridoma growth rate, maximum viable and total cell yield, and specific antibody production rate is presented. The specific growth rate varied in a Monod fashion with initial serum levels (2-10ยฐ/0 FCS), giving K,,, = 1.6 v/v% a