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Reinvestigation of the Mannich reaction of 4-nitrophenylacetic acid and 2,4-dinitrophenylacetic acid

โœ Scribed by Schauble, J. Herman.; Hertz, Elisabeth.

Book ID
126929389
Publisher
American Chemical Society
Year
1970
Tongue
English
Weight
578 KB
Volume
35
Category
Article
ISSN
0022-3263

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The Mannich reaction plays an essential role in the biosynthesis2 and laboratory synthesis of important nitrogenous substances. 3 In spite of the importance of the reaction, a satisfactory mechanism has not been elucidated. Several different mechanisms probably operate, depending upon pH and the nat