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Regulatory T cells: Nurtured by TGFβ

✍ Scribed by Bird, Lucy

Book ID
109956354
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
210 KB
Volume
10
Category
Article
ISSN
1474-1741

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## Abstract Scurfy mice have a deletion in the forkhead domain of the forkhead transcription factor p3 (Foxp3), fail to develop thymic‐derived, naturally occurring Foxp3^+^ regulatory T cells (nTreg), and develop a fatal lymphoproliferative syndrome with multi‐organ inflammation. Transfer of thymic