Human regulatory T cells and autoimmunit
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Cristina M. Costantino; Clare M. Baecher-Allan; David A. Hafler
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Article
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2008
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John Wiley and Sons
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English
⚖ 136 KB
👁 1 views
## Abstract CD4^+^CD25^+^ regulatory T cells (Treg) appear to be critical in regulating immune responses to self‐antigens. Treg deficiency is associated with several human autoimmune diseases. Although substantial progress has been made in the study of murine and human Treg, their fundamental mecha