## Abstract Treg can suppress autoimmune diseases such as type 1 diabetes, but their __in vivo__ activity during suppression remains poorly characterized. In type 1 diabetes, Treg activity has been demonstrated in the pancreatic lymph node, but little has been studied in the pancreas, the site of a
Regulatory T-cells in type 1 diabetes
β Scribed by Amy E. Juedes; Matthias G. von Herrath
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 133 KB
- Volume
- 20
- Category
- Article
- ISSN
- 1520-7552
- DOI
- 10.1002/dmrr.508
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Immune regulation is a complex process that depends on the maintenance of self tolerance while retaining robust immune responses against microbes. The emergence of Treg as a central mechanism for immune regulation has generated a new paradigm where Tregβresistant memory T cells and/or β
## Abstract Recent studies have revealed that Foxp3^+^CD25^+^CD4^+^ regulatory T cells (Tregs), which are physiologically engaged in the maintenance of immunological selfβtolerance, play critical roles for the control of antitumor immune responses. For example, a large number of Foxp3^+^Tregs infil