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Peptide-activated double-negative T cells can prevent autoimmune type-1 diabetes development

✍ Scribed by Megan S. Ford; Wenhao Chen; Sophie Wong; Carmen Li; Ramesh Vanama; Alisha R. Elford; Sylvia L. Asa; Pamela S. Ohashi; Li Zhang


Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
235 KB
Volume
37
Category
Article
ISSN
0014-2980

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✍ Menachem Bitan; Lola Weiss; Michael Zeira; Shoshana Reich; Orit Pappo; Israel Vl 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 216 KB

## Abstract ## Background Heparanase is an endo‐β‐D‐glucuronidase that cleaves heparan sulfate saccharide chains. The enzyme promotes cell adhesion, migration and invasion, and was shown to play a significant role in cancer metastasis and angiogenesis. ## Methods The present study focuses on the