Trimethoprim inhibits dihydrofolate reductase. Mutations conferring trimethorpim-resistance on E coli K12 result in either an altered reductase with decreased affinity for the drug, or in 2-30 fold higher levels of the enzyme. Studies of the latter class of mutants indicate that dihydrofolate reduct
โฆ LIBER โฆ
Regulatory Mechanisms for Synthesis of Capsular Polysaccharide in Mucoid Mutants of Escherichia coli K12
โ Scribed by Alvin Markovitz
- Book ID
- 123657675
- Publisher
- National Academy of Sciences
- Year
- 1964
- Tongue
- English
- Weight
- 311 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0027-8424
- DOI
- 10.2307/72178
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