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Regulation of tumor angiogenesis by thrombospondin-1

โœ Scribed by Bin Ren; Karen O. Yee; Jack Lawler; Roya Khosravi-Far

Book ID
113486617
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
248 KB
Volume
1765
Category
Article
ISSN
0304-419X

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The role of thrombospondin-1 in tumor pr
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โœ George P. Tuszynski; Roberto F. Nicosia ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 834 KB

Thrombospondin (TSP-1) is a large glycoprotein secreted by platelets and synthesized by many cell types, including endothelial and tumor cells. Although controversy exists about the biological function of TSP-1, the following observations suggest that TSP-1 may potentiate tumor progression. (1) Tumo