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Thrombospondin-1 as an endogenous inhibitor of angiogenesis and tumor growth

✍ Scribed by Jack Lawler

Book ID
114777993
Publisher
Carol Davila University of Medicine Bucharest, Romania
Year
2002
Tongue
English
Weight
784 KB
Volume
6
Category
Article
ISSN
1582-1838

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✍ George P. Tuszynski; Roberto F. Nicosia πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 834 KB

Thrombospondin (TSP-1) is a large glycoprotein secreted by platelets and synthesized by many cell types, including endothelial and tumor cells. Although controversy exists about the biological function of TSP-1, the following observations suggest that TSP-1 may potentiate tumor progression. (1) Tumo