Regulation of transferrin receptors by iron in human erythroblasts
โ Scribed by Yasunobu Abe; Koichiro Muta; Junji Nishimura; Hajime Nawata
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 526 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0361-8609
No coin nor oath required. For personal study only.
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## Abstract In human beings, serum transferrin levels increase during iron deficiency and decrease with iron overload. Yet, whether or not iron levels actually affect the synthesis of transferrin in human liver cells is not known. In previous studies, iron was shown to suppress the expression of ch
## The hepatic uptake of transferrin-bound iron by a Iron is required for the synthesis of many heme and nontransferrin receptor (NTR)-mediated process was non-heme proteins and enzymes necessary for cellular investigated using the human hepatoma cell line HuH7. growth and metabolism. Most cells t