Regulation of Her2/neu promoter activity
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Denis G. Bosc; Ralf Janknecht
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Article
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2002
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John Wiley and Sons
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English
β 266 KB
Overexpression of the HER2/Neu receptor is correlated to a poor prognosis in tumor patients and leads to stimulation of mitogen-activated protein kinase (MAPK) signaling pathways, which in turn activate transcription factors, such as the ETS protein ER81. Here, we have analyzed whether, on the other