Regulation of Ribonucleotide Reductase in Response to Iron Deficiency
✍ Scribed by Nerea Sanvisens; M. Carmen Bañó; Mingxia Huang; Sergi Puig
- Book ID
- 116755114
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 923 KB
- Volume
- 44
- Category
- Article
- ISSN
- 1097-2765
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Mammalian ribonucleotide reductase catalyzes the rate-limiting for the de novo synthesis 2'-deoxyribonucleoside 5'-triphosphates. There is some suggestion that this step may also be the rate-limiting step of DNA synthesis. It is apparent that the level of the enzyme, ribonucleotide reductase, varies