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Regulation of retinoblastoma protein stability and function by the COP signalosome

โœ Scribed by Martin S. Buckley; Zakir Ullah; Geoffrey L. Williams; David N. Arnosti; R. William Henry

Book ID
116975745
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
54 KB
Volume
295
Category
Article
ISSN
0012-1606

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โœ Jonathan M. Horowitz ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 908 KB

The product of the retinoblastoma gene ( R B I ) is believed to function as a negative regulator of cell growth. Recent experimental results suggest that RBI may exert its growth-suppressing activity by regulating the transcription of a variety of growthrelated genes, including FOS, MYC, and TGFB /.