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Regulation of renin enhancer activity by nuclear factor I and Sp1/Sp3

✍ Scribed by Li Pan; Sean T. Glenn; Craig A. Jones; Richard M. Gronostajski; Kenneth W. Gross

Book ID
114147712
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
627 KB
Volume
1625
Category
Article
ISSN
0167-4781

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Specificity of transcriptional regulatio
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✍ Alia Al-Sarraj; Regina M. Day; Gerald Thiel πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 246 KB

## Abstract The transcription factors Sp1, Sp3, and Egr‐1 bind with their zinc finger DNA‐binding domains to GC‐rich sequences in the regulatory regions of their target genes. The similarity of the DNA‐binding sites of Sp1, Sp3, and Egr‐1 has triggered the hypothesis that they compete for the same