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Regulation of physiological responses to continuous and intermittent hypoxia by hypoxia-inducible factor 1

✍ Scribed by Gregg L. Semenza


Book ID
110109731
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
217 KB
Volume
91
Category
Article
ISSN
0958-0670

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## Abstract Sleep‐disordered breathing with recurrent apnea is associated with intermittent hypoxia (IH). Cardiovascular morbidities caused by IH are triggered by increased generation of reactive oxygen species (ROS) by pro‐oxidant enzymes, especially NADPH oxidase‐2 (Nox2). Previous studies showed