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Regulation of NOTCH signaling by reciprocal inhibition of HES1 and Deltex 1 and its role in osteosarcoma invasiveness

✍ Scribed by Zhang, P; Yang, Y; Nolo, R; Zweidler-McKay, P A; Hughes, D P M

Book ID: 109972731
Publisher: Nature Publishing Group
Year: 2010
Tongue: English
Weight: 740 KB
Volume: 29
Category: Article
ISSN: 0950-9232
DOI: 10.1038/onc.2010.62

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## Abstract Notch signaling is involved in a variety of cellular processes, such as cell fate specification, differentiation, proliferation, and survival. Notch‐1 over‐expression has been reported in prostate cancer metastases. Likewise, Notch ligand Jagged‐1 was found to be over‐expressed in metas