Regulation of hippocampal neuronal diffe
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Paul Castella; John A. Wagner; Michael Caudy
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Article
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1999
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John Wiley and Sons
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English
⚖ 244 KB
👁 2 views
HES-1 is a vertebrate homologue of the Drosophila basic helix-loop-helix (bHLH) protein Hairy, a transcriptional repressor that negatively regulates neuronal differentiation. HES-1 expression in neuronal precursors precedes and represses the expression of the neuronal commitment gene MASH-1, a bHLH